The attackers escaped after setting the PML-N office in Hyderabad on fire, which was located on the first floor of the district council building.
The General Secretary of the PML-N, Hyderabad, said that party chief Nawaz Sharif's posters and pictures were also being burnt in different parts of the city.
Nawab Shah, Kandhkot, Jacobabad and Khairpur were among the other cities where PML-N offices were targeted and set ablaze, the report said
Sindh Home Minister Manzoor Wasan has ordered for a judicial inquiry into the incidents and asked the Sindh police Inspector-General to submit the report on priority basis.