According to details, the powerful blast occurred in a lawn near Cafeteria.
At least eight people were injured in the blast. The injured have been shifted to hospital.
Police and rangers cordoned off the site immediately after the blast and conducted search operation.
The students staged protest against the security conditions in the University.
SP Raja Omar Khitab said that 1-kg explosive used in the blast. He said that it was a time device and installed in a tree.
Talking to Aaj News, Registrar UoK said that examinations cancelled which was due today.
Karachi University will remain closed for three days. This was announced by the Registrar of the institution. Later, the decision was taken back.