"Mr Heath Ledger died as the result of acute intoxication by the combined effects of oxycodone, hydrocodone, diazepam, temazepam, alprazolam, and doxylamine," city Chief Medical Examiner Charles Hirsch said in a statement.
"We have concluded that the manner of death is accident, resulting from the abuse of prescription medications."
The cause of the 28-year-old's death had been shrouded in mystery, with an initial post-mortem inconclusive and conflicting speculation that he was a drug user and suffering from pneumonia.
Copyright AFP (Agence France-Presse), 2008