PPP leader Zulfiqar Mirza resigned from his party's post  and ministry.Addressing press conference in Karachi , Zulfiqar Mirza strongly criticized MQM and Interior Minister Rehman Malik and said If Country bears any loss ,Rehman Malik would be responsible for that.He further said that Rehman Malik was providing shelter to Bhai Log. He further said that MQM Chief Altaf Hussain had met with me in London and accused that Altaf Hussain said to me that America has decided to break Pakistan and MQM was along with USA .He further accused that Police man Ishtiaq was a target killer and assist MQM in killings. Zulfiqar Mirza said that twenty five target killers have been released on payroll.