Misbah ul Haq scored 47 and Steven Finn took four wickets as Pakistan were bowled out for 230.
Earlier England set Pakistan a target of 251 runs to clinch the second one day international cricket match.
Alastair Cook top-scored for England with 102 as the tourists made 251-4 after winning the toss. Aizaz Cheema with 2-49 was Pakistan's most impressive bowler.