Born to an educated Syed family, Salim Nasir had all the ingredients necessary to fulfill his ambition. He had a successful career in TV and Film.

Nasir made his professional cinematic debut in film called 'Zaib-un-nisa '. He earned accolades for his acting skills in many plays, especially Aakhri Chatan, Nishan-e-Haider, Un Kahi, Dastak and Aangan Terha.

Salim Nasir was honored with Pakistan's highest achievement award in the field of acting,'The President's Pride of Performance Award'. Presented to his family after his death. At the age of 45 years, Nasir suffered a heart attack on 24 September 1989. On Thursday, October 19 he experienced signs of extreme heart congestion around noon. He was rushed to hospital but expired before any medical treatment could be provided.